Healthy cell function relies on well orchestrated gene activity. Via a fantastically complex network of interactions, around 30,000 genes cooperate to maintain this delicate balance in each of the 37.2 trillion cells in the human body.
Broadly speaking, cancer is a disruption of this balance by genetic changes, or mutations. Mutations can trigger over-activation of genes that normally instruct cells to divide, or inactivation of genes that suppress the development of cancer. When a mutated cell divides, it passes the mutation down to its daughter cells. This leads to the accumulation of non-functioning, abnormal cells that we recognise as cancer.
Our laboratory is focused on understanding how one particular cancer – chronic myeloid leukemia or CML – works. Each year more than 700 patients in the UK – and over 100,000 worldwide – are diagnosed with CML. After recent advances, almost 90% of patients under the age of 65
To read more see the full post at: Chronic Myeloid Leukemia: How Big Data Is Helping In The Fight - ReliaWire